From Baseball-Reference.com:

1960 – A record opening day crowd of 53,563 at Briggs Stadium sees the Detroit Tigers chalk up their third straight win, 6 – 5, against the Chicago White Sox. Recently-acquired Rocky Colavito blasts a home run in his first at-bat with Detroit, and Eddie Yost adds a home run in the 5th inning.

Jim Bunning got the Opening Day start, Tom Morgan notched the win.

Here’s the boxscore.